OxyFile #176
UI - 95101410
AU - Bocci V
AU - Luzzi E
AU - Corradeschi F
AU - Paulesu L
TI - Studies on the biological effects of ozone: 5. Evaluation of
immunological parameters and tolerability in normal volunteers
receiving ambulatory autohaemotherapy.
AD - Faculties of Pharmacy, Institute of General Physiology, Siena,
Italy.
AB - Autohaemotherapy, after a bland treatment ex vivo of blood with
ozone, is a fairly unknown medical procedure claimed to have
therapeutic value in viral diseases and neoplasms. Having already
shown that ozone acts as a mild inducer of cytokines, we have
undertaken an investigation in normal rabbits and in normal
volunteers aiming to evaluate eventual changes of some cytokine
levels in plasma as well as of immunological parameters such as
the Mx protein, neopterin, beta 2-microglobulin and of some
acute-phase proteins after single or repeated autohaemotherapy.
We have also evaluated the potential development of of
side-effects. This study is the first one to show that
autohaemotherapy can activate an immunological marker in normal
subjects without procuring any toxic effects.
PT - JOURNAL ARTICLE
LA - Eng
SO - Biotherapy 1993-94;7(2):83-90